Ingredient library

What is in HydroSure, and why.

HydroSure has six actives, each printed on the label with its exact amount. This library explains each one in plain words and says why it is in the formula.

HydroSure

Six actives, 21 g per serving.

We list them in label order, largest dose first. The amounts match the Supplement Facts printed on the tub.

Six glass dishes of white powders and crystals in two rows on pale stone.

L-Alanine

What it is: An amino acid your body makes and uses to build protein. It is a different molecule from beta-alanine, the pre-workout ingredient known for a tingling feeling.
Its role: In cell studies, cells take up alanine as an osmolyte when they need to adjust their volume. In normal metabolism it also helps carry nitrogen from muscle to the liver.
Why it is in HydroSure: It shares the largest dose with creatine. Its osmolyte role comes mostly from cell studies, and research on L-alanine and exercise performance is limited, so we include it for its osmolyte role.

Creatine monohydrate

What it is: A compound your body makes from amino acids and stores mostly in skeletal muscle. Creatine monohydrate is one of the most studied compounds in sports nutrition.
Its role: Muscle cells pull creatine in through a dedicated transporter. Creatine supports high-intensity exercise performance.*
Why it is in HydroSure: Of the six actives, creatine has the most direct human research on body water. In one controlled study, which began with a week at 25 g a day, creatine raised total body water while the split between water inside and outside cells stayed the same. 5 g a day is a well-studied daily amount; without the high-dose week, muscle stores fill over about 3 to 4 weeks.

Glycine

What it is: The simplest amino acid. Your body makes it, and it is part of the protein you eat.
Its role: Cells can use it as a compatible osmolyte, one that builds up without disturbing the proteins that do the cell's work. Most of that evidence comes from cell studies and other species. Glycine also acts as a signaling molecule in the nervous system.
Why it is in HydroSure: At 4 g it is the third largest dose in the formula. Much of the exercise research on glycine is still preclinical, so we include it for its role as an osmolyte.

Taurine

What it is: One of the most abundant free amino acids in the body. Muscle, heart and brain tissue hold especially high levels of it.
Its role: An osmolyte that helps cells regulate their volume. Cells pull taurine in through a dedicated transporter and keep it at levels far above those in the blood.
Why it is in HydroSure: Taurine is one of the main osmolytes in muscle. Research on taurine and exercise performance is mixed, so we include it for its role in cell volume.

L-Glutamine

What it is: The most abundant free amino acid in the body.
Its role: In cell and liver studies, glutamine is one of the most studied amino acids for cell swelling. As cells take it up, water follows. About two thirds of an oral dose is used by the gut and liver first.
Why it is in HydroSure: It adds to the osmolyte pool at a supporting dose. Most of the research on glutamine and cell swelling is mechanistic, and we describe it that way.

Betaine

Also called trimethylglycine, or TMG

What it is: A small molecule your body gets from food and also makes from choline.
Its role: An osmolyte that helps cells defend their volume under stress. It is also a methyl donor, which means it hands off a small chemical group the body uses in normal metabolism.
Why it is in HydroSure: It plays a supporting role. Studies of betaine and strength or power used about 2.5 g a day, more than the 1 g here. We include it for its osmolyte and methyl donor roles and make no performance claim for it.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Beyond the actives

The rest of the label.

Besides the six actives, the label lists one other ingredient.

Other ingredients
Silicon dioxide, which keeps the powder free-flowing.
Added electrolytes
None. HydroSure has no added sodium, potassium or magnesium. If you sweat heavily for long periods, you can get electrolytes from food or a separate product.
Stimulants
None. There is no caffeine or other stimulant on the label.
Flavors and sweeteners
The label lists none.

Supplement Facts

Read it as printed.

The product page sets out the Supplement Facts exactly as they appear on the tub. The HydroSure page shows the cell biology the formula is built on.

View Supplement Facts How it works

Directions: Mix 2 scoops in 64 ounces of water.
Caution: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Net weight: 23.3 oz (660 g)
Distributed by: VitaNouvelle LifeScience, Richardson, TX